Irremediableness

I fall sick of Sin, and am bedded and bedrid, buried and putrified in the practise of Sin, and all this while have no presage, no pulse, no sense of my sicknesse; O heighth, O depth of misery, where the first Symptome of the sicknes is Hell, and where I never see the fever of lust, of envy, of ambition, by any other light, than the darknesse and horror of Hell it selfe; and where the first Messenger that speaks to me doth not say, Thou mayest die, no, nor Thou must die, but Thou art dead: and where the first notice, that my Soule hath of her sicknes, is irrecoverablenes, iremediablenes.

John Donne, Devotions upon Emergent Occasions (1624), Expostulation 1